Chromatin is the DNA/Protein material which makes up the chromosomes, its modification plays a significant role in the regulation of gene expression.
Latest Chromatin Publications:
Transcription factor 7-like 2 (TCF7L2) regulates activin receptor-like kinase 1 (ALK1)/Smad1 pathway for development of diabetic nephropathy. Smad1 has previously been shown to play a key role in the development of ... Araoka T, Abe H, Tominaga T, Mima A, Matsubara T, Murakami T, Kishi S, Nagai K, Doi T,http://dx.doi.org/10.1007/s10059-010-0109-9 Mol Cells. 2010 Aug 23.
Apoptosis and DNA damage in human spermatozoa. DNA damage is frequently encountered in spermatozoa of subfertile males ... Aitken RJ, Koppers AJ,http://dx.doi.org/10.1038/aja.2010.68 Asian J Androl. 2010 Aug 30.
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. DNA double-strand break (DSB) repair occurs within chromatin and can be ... Miller KM, Tjeertes JV, Coates J, Legube G, Polo SE, Britton S, Jackson SP,http://dx.doi.org/10.1038/nsmb.1899 Nat Struct Mol Biol. 2010 Aug 29.
Heat shock transcription factor 1 localizes to the sex chromatin during meiotic repression. Heat shock factor 1 (HSF1) is an important transcription factor in ... Akerfelt M, Vihervaara A, Laiho A, Conter A, Christians ES, Sistonen L, Henriksson E,http://dx.doi.org/10.1074/jbc.M110.157552 J Biol Chem. 2010 Aug 27.
YIA1 Interaction between HDAC3 and XBP1 is critical in maintainence of endothelial integrity. Histone deacetylases (HDACs) play a crucial role in transcriptional ... Martin D, Li H, Zampetaki A, Hu Y, Zeng L, Xu Q,http://dx.doi.org/10.1136/hrt.2010.205781.1 Heart. 2010 Sep;96(17):e9.
BAS/BSCR30 Crucial roles of Cbx3 identified by nuclear proteomics in smooth muscle differentiation from stem cells and vascular injury-induced neointima formation. Rationale Our previous studies have developed an efficiency method for ... Xiao Q, Wang G, Bai X, Yin X, Luo Z, Mayr M, Ye S, Xu Q,http://dx.doi.org/10.1136/hrt.2010.205781.41 Heart. 2010 Sep;96(17):e21.
Synthesis of the steroidal glycoside (25R)-3beta,16beta-diacetoxy-12,22-dioxo-5alpha-cholestan-26-yl beta-d-glucopyranoside and its anti-cancer properties on cervicouterine HeLa, CaSki, and ViBo cells. The synthesis of the new glycoside ... Fernandez-Herrera MA, Mohan S, Lopez-Munoz H, Hernandez-Vazquez JM, Perez-Cervantes E, Escobar-Sanchez ML, Sanchez-Sanchez L, Regla I, Pinto BM, Sandoval-Ramirez J,http://dx.doi.org/10.1016/j.ejmech.2010.07.051 Eur J Med Chem. 2010 Aug 11.
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network. BACKGROUND & AIMS:: The Notch receptor family regulates cell fate through ... Ohashi S, Natsuizaka M, Yashiro-Ohtani Y, Kalman RA, Nakagawa M, Wu L, Klein-Szanto AJ, Herlyn M, Diehl JA, Katz JP, Pear WS, Seykora JT, Nakagawa H,http://dx.doi.org/10.1053/j.gastro.2010.08.040 Gastroenterology. 2010 Aug 26.
Linker histone subtypes are not generalized gene repressors. Antibodies to the six chicken histone H1 subtypes and the variant histone ... Trollope AF, Sapojnikova N, Thorne AW, Crane-Robinson C, Myers FA,http://dx.doi.org/10.1016/j.bbagrm.2010.08.007 Biochim Biophys Acta. 2010 Aug 25.
Crystal Structures of Nucleosome Core Particles Containing the '601' Strong Positioning Sequence. By defining histone-DNA context and modulating access to specific sites, ... Vasudevan D, Chua EY, Davey CA,http://dx.doi.org/10.1016/j.jmb.2010.08.039 J Mol Biol. 2010 Aug 25.
Bcl3-dependent Stabilization of CtBP1 is Crucial for the Inhibition of Apoptosis and Tumor Progression in Breast Cancer. B-cell lymphoma 3 (Bcl3) is a proto-oncogene upregulated in a wide range ... Choi HJ, Lee JM, Kim H, Nam HJ, Shin HJ, Kim D, Ko E, Noh DY, Kim KI, Kim JH, Baek SH,http://dx.doi.org/10.1016/j.bbrc.2010.08.084 Biochem Biophys Res Commun. 2010 Aug 25.
Control of embryonic stem cell identity by nucleosome remodeling enzymes. Embryonic stem (ES) cells are pluripotent cells that can self-renew ... Fazzio TG, Panning B,http://dx.doi.org/10.1016/j.gde.2010.08.001 Curr Opin Genet Dev. 2010 Aug 25.
Structural Analysis of HMGD-DNA Complexes Reveal Influence of Intercalation on Sequence Selectivity and DNA Bending. The ubiquitous eukaryotic High-Mobility-Group-Box (HMGB) chromosomal ... Churchill ME, Klass J, Zoetewey DL,http://dx.doi.org/10.1016/j.jmb.2010.08.031 J Mol Biol. 2010 Aug 24.
L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions. ABSTRACT: BACKGROUND: The L1 cell adhesion molecule (L1CAM) was originally ... Pfeifer M, Schirmer U, Geismann C, Schafer H, Sebens S, Altevogt P,http://dx.doi.org/10.1186/1471-2199-11-64 BMC Mol Biol. 2010 Aug 27;11(1):64.
Complexity of Polycomb group function - diverse mechanisms of target specificity. Epigenetic regulation of gene expression has become relevant to nearly all ... Trask MC, Mager J,http://dx.doi.org/10.1002/jcp.22395 J Cell Physiol. 2010 Aug 26.