The structure of chromatin its self is regulated primarily through acylation and methylation
Latest Chromatin Structure Publications:
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Previous studies have led to a picture wherein the replication of DNA ... Sekedat MD, Fenyo D, Rogers RS, Tackett AJ, Aitchison JD, Chait BT,http://dx.doi.org/10.1038/msb.2010.8 Mol Syst Biol. 2010;6:353. Epub 2010 Mar 9.
Does ciprofloxacin have an obverse and a reverse? Ciprofloxacin is an antibiotic that belongs to fluoroquinoles, ... Kloskowski T, Gurtowska N, Drewa T,http://dx.doi.org/10.1016/j.pupt.2010.02.005 Pulm Pharmacol Ther. 2010 Mar 4.
CHD1 Remodelers Maintain Open Chromatin and Regulate the Epigenetics of Differentiation. Eukaryotic DNA is packaged around octamers of histone proteins into ... Persson J, Ekwall K,http://dx.doi.org/10.1016/j.yexcr.2010.02.029 Exp Cell Res. 2010 Mar 5.
A paucity of heterochromatin at functional human neocentromeres. ABSTRACT: BACKGROUND: Centromeres are responsible for the proper ... Alonso A, Hasson D, Cheung F, Warburton PE,http://dx.doi.org/10.1186/1756-8935-3-6 Epigenetics Chromatin. 2010 Mar 8;3(1):6.
Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5. Correct hematopoietic differentiation requires the tightly regulated ... Walter K, Cockerill PN, Barlow R, Clarke D, Hoogenkamp M, Follows GA, Richards SJ, Cullen MJ, Bonifer C, Tagoh H,http://dx.doi.org/10.1038/onc.2010.56 Oncogene. 2010 Mar 8.
Nucleosome dynamics define transcriptional enhancers. Chromatin plays a central role in eukaryotic gene regulation. We performed ... He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q, Zhang Y, Xu K, Ni M, Lupien M, Mieczkowski P, Lieb JD, Zhao K, Brown M, Liu XS,http://dx.doi.org/10.1038/ng.545 Nat Genet. 2010 Mar 7.
CREBBP Re-arrangements affect protein function and lead to aberrant neuronal differentiation. Biallelic inactivation of the CREB-binding protein (CREBBP) a ... Sharma N, Jadhav SP, Bapat SA,http://dx.doi.org/10.1016/j.diff.2010.02.001 Differentiation. 2010 Mar 5.
Assembly dynamics of PML nuclear bodies in living cells. ABSTRACT: The mammalian cell nucleus contains a variety of organelles or ... Brand P, Lenser T, Hemmerich P,http://dx.doi.org/10.1186/1757-5036-3-3 PMC Biophys. 2010 Mar 5;3(1):3.
Detection and Quantification of DNA Strand Breaks Using the ROPS (Random Oligonucleotide Primed Synthesis) Assay. DNA double strand breaks (DSBs) arise from spontaneous DNA damage due to ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_17 Methods Mol Biol. 2010;631:237-42.
Detection of changes in global genome methylation using the Cytosine-extension assay. Methylation is a reversible covalent chemical modification of DNA intended ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_4 Methods Mol Biol. 2010;631:33-9.
Analysis of Locus-Specific Changes in Methylation Patterns Using a COBRA (Combined Bisulfite Restriction Analysis) Assay. DNA methylation is a major mechanism for the reversible control of gene ... Boyko A, Kovalchuk I,http://dx.doi.org/10.1007/978-1-60761-646-7_3 Methods Mol Biol. 2010;631:23-31.
The impact of histone post-translational modifications on developmental gene regulation. Eukaryotic genomic DNA is orderly compacted to fit into the nucleus and to ... Cruickshank MN, Besant P, Ulgiati D,http://dx.doi.org/10.1007/s00726-010-0530-6 Amino Acids. 2010 Mar 5.
Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6. The minichromosome maintenance (Mcm) 2-7 complex is the replicative ... Wei Z, Liu C, Wu X, Xu N, Zhou B, Liang C, Zhu G,http://dx.doi.org/10.1074/jbc.C109.094599 J Biol Chem. 2010 Mar 4.
Symposium 2: Modern approaches to nutritional research challenges Nutritional developmental epigenomics: immediate and long-lasting effects. The phenotype of an individual is the result of complex interactions ... Attig L, Gabory A, Junien C,http://dx.doi.org/10.1017/S002966511000008X Proc Nutr Soc. 2010 Mar 5:1-11.
A plant-specific histone H3 lysine-4 demethylase represses the floral transition in Arabidopsis. Summary Histone demethylation regulates chromatin structure and gene ... Yang W, Jiang D, Jiang J, He Y,http://dx.doi.org/10.1111/j.1365-313X.2010.04182.x Plant J. 2010 Feb 24.