Chromatin has a major role in gene regulation, the structure of chromatin its self is regulated primarily through acylation and methylation
Latest Chromatin Regulation Publications:
YIA1 Interaction between HDAC3 and XBP1 is critical in maintainence of endothelial integrity. Histone deacetylases (HDACs) play a crucial role in transcriptional ... Martin D, Li H, Zampetaki A, Hu Y, Zeng L, Xu Q,http://dx.doi.org/10.1136/hrt.2010.205781.1 Heart. 2010 Sep;96(17):e9.
BAS/BSCR30 Crucial roles of Cbx3 identified by nuclear proteomics in smooth muscle differentiation from stem cells and vascular injury-induced neointima formation. Rationale Our previous studies have developed an efficiency method for ... Xiao Q, Wang G, Bai X, Yin X, Luo Z, Mayr M, Ye S, Xu Q,http://dx.doi.org/10.1136/hrt.2010.205781.41 Heart. 2010 Sep;96(17):e21.
Linker histone subtypes are not generalized gene repressors. Antibodies to the six chicken histone H1 subtypes and the variant histone ... Trollope AF, Sapojnikova N, Thorne AW, Crane-Robinson C, Myers FA,http://dx.doi.org/10.1016/j.bbagrm.2010.08.007 Biochim Biophys Acta. 2010 Aug 25.
Crystal Structures of Nucleosome Core Particles Containing the '601' Strong Positioning Sequence. By defining histone-DNA context and modulating access to specific sites, ... Vasudevan D, Chua EY, Davey CA,http://dx.doi.org/10.1016/j.jmb.2010.08.039 J Mol Biol. 2010 Aug 25.
Control of embryonic stem cell identity by nucleosome remodeling enzymes. Embryonic stem (ES) cells are pluripotent cells that can self-renew ... Fazzio TG, Panning B,http://dx.doi.org/10.1016/j.gde.2010.08.001 Curr Opin Genet Dev. 2010 Aug 25.
L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions. ABSTRACT: BACKGROUND: The L1 cell adhesion molecule (L1CAM) was originally ... Pfeifer M, Schirmer U, Geismann C, Schafer H, Sebens S, Altevogt P,http://dx.doi.org/10.1186/1471-2199-11-64 BMC Mol Biol. 2010 Aug 27;11(1):64.
Complexity of Polycomb group function - diverse mechanisms of target specificity. Epigenetic regulation of gene expression has become relevant to nearly all ... Trask MC, Mager J,http://dx.doi.org/10.1002/jcp.22395 J Cell Physiol. 2010 Aug 26.
Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor. Although metastasis accounts for >90% of cancer-related deaths, no ... Yadav VR, Sung B, Prasad S, Kannappan R, Cho SG, Liu M, Chaturvedi MM, Aggarwal BB,http://dx.doi.org/10.1007/s00109-010-0669-3 J Mol Med. 2010 Aug 27.
A positive role for c-Abl in Atm and Atr activation in DNA damage response. DNA damage triggers Atm- and/or Atr-dependent signaling pathways to ... Wang X, Zeng L, Wang J, Chau JF, Lai KP, Jia D, Poonepalli A, Hande MP, Liu H, He G, He L, Li B,http://dx.doi.org/10.1038/cdd.2010.106 Cell Death Differ. 2010 Aug 27.
Involvement of NF-kappaB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial-mesenchymal transition of breast cancer cells. The epithelial-mesenchymal transition (EMT) induced by chemotherapeutic ... Li QQ, Chen ZQ, Cao XX, Xu JD, Xu JW, Chen YY, Wang WJ, Chen Q, Tang F, Liu XP, Xu ZD,http://dx.doi.org/10.1038/cdd.2010.103 Cell Death Differ. 2010 Aug 27.
The role of chromatin condensation during granulopoiesis in the regulation of gene cluster expression. Changes in nuclear architecture play an important role in the regulation ... Stejskal S, Koutna I, Matula P, Rucka Z, Danek O, Maska M, Kozubek M,http://dx.doi.org/10.4161/epi.5.8.13183 Epigenetics. 2010 Nov 28;5(8).
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Multipotent progenitor cells of the cerebral cortex balance self-renewal ... Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, Livesey FJ,http://dx.doi.org/10.1073/pnas.1002530107 Proc Natl Acad Sci U S A. 2010 Aug 23.
Structure of RCC1 chromatin factor bound to the nucleosome core particle. The small GTPase Ran enzyme regulates critical eukaryotic cellular ... Makde RD, England JR, Yennawar HP, Tan S,http://dx.doi.org/10.1038/nature09321 Nature. 2010 Aug 25.
Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing. Microarrays are powerful tools to probe genome-wide replication kinetics. ... Yang SC, Rhind N, Bechhoefer J,http://dx.doi.org/10.1038/msb.2010.61 Mol Syst Biol. 2010 Aug 24;6:404.
The X as Model for RNA's Niche in Epigenomic Regulation. The X-linked region now known as the "X-inactivation center" (Xic) was ... Lee JT,http://dx.doi.org/10.1101/cshperspect.a003749 Cold Spring Harb Perspect Biol. 2010 Aug 25.