Chromatin has various functions including ensuring the stability of DNA, affecting gene expression, and chromosome replication
Latest Chromatin Function Publications:
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. DNA double-strand break (DSB) repair occurs within chromatin and can be ... Miller KM, Tjeertes JV, Coates J, Legube G, Polo SE, Britton S, Jackson SP,http://dx.doi.org/10.1038/nsmb.1899 Nat Struct Mol Biol. 2010 Aug 29.
BAS/BSCR30 Crucial roles of Cbx3 identified by nuclear proteomics in smooth muscle differentiation from stem cells and vascular injury-induced neointima formation. Rationale Our previous studies have developed an efficiency method for ... Xiao Q, Wang G, Bai X, Yin X, Luo Z, Mayr M, Ye S, Xu Q,http://dx.doi.org/10.1136/hrt.2010.205781.41 Heart. 2010 Sep;96(17):e21.
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network. BACKGROUND & AIMS:: The Notch receptor family regulates cell fate through ... Ohashi S, Natsuizaka M, Yashiro-Ohtani Y, Kalman RA, Nakagawa M, Wu L, Klein-Szanto AJ, Herlyn M, Diehl JA, Katz JP, Pear WS, Seykora JT, Nakagawa H,http://dx.doi.org/10.1053/j.gastro.2010.08.040 Gastroenterology. 2010 Aug 26.
Bcl3-dependent Stabilization of CtBP1 is Crucial for the Inhibition of Apoptosis and Tumor Progression in Breast Cancer. B-cell lymphoma 3 (Bcl3) is a proto-oncogene upregulated in a wide range ... Choi HJ, Lee JM, Kim H, Nam HJ, Shin HJ, Kim D, Ko E, Noh DY, Kim KI, Kim JH, Baek SH,http://dx.doi.org/10.1016/j.bbrc.2010.08.084 Biochem Biophys Res Commun. 2010 Aug 25.
Control of embryonic stem cell identity by nucleosome remodeling enzymes. Embryonic stem (ES) cells are pluripotent cells that can self-renew ... Fazzio TG, Panning B,http://dx.doi.org/10.1016/j.gde.2010.08.001 Curr Opin Genet Dev. 2010 Aug 25.
Complexity of Polycomb group function - diverse mechanisms of target specificity. Epigenetic regulation of gene expression has become relevant to nearly all ... Trask MC, Mager J,http://dx.doi.org/10.1002/jcp.22395 J Cell Physiol. 2010 Aug 26.
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Multipotent progenitor cells of the cerebral cortex balance self-renewal ... Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, Livesey FJ,http://dx.doi.org/10.1073/pnas.1002530107 Proc Natl Acad Sci U S A. 2010 Aug 23.
NFX1 plays a role in HPV16 E6 activation of NF{kappa}B activity. High risk human papillomavirus (HR HPV) requires differentiating ... Xu M, Katzenellenbogen RA, Grandori C, Galloway DA,http://dx.doi.org/10.1128/JVI.00538-10 J Virol. 2010 Aug 25.
Progesterone receptor membrane component-1 expression and putative function in bovine oocyte maturation, fertilization and early embryonic development. Although mRNA encoding progesterone receptor membrane component-1 (PGRMC1) ... Luciano AM, Lodde V, Franciosi F, Ceciliani F, Peluso JJ,http://dx.doi.org/10.1530/REP-10-0218 Reproduction. 2010 Aug 25.
Plant stem cell niches: from signalling to execution. The shoot and root meristems contain small populations of stem cells that ... Sablowski R,http://dx.doi.org/10.1016/j.pbi.2010.08.001 Curr Opin Plant Biol. 2010 Aug 23.
MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. BACKGROUND:: MicroRNAs (miRNAs) are small noncoding RNAs that regulate the ... Majid S, Dar AA, Saini S, Yamamura S, Hirata H, Tanaka Y, Deng G, Dahiya R,http://dx.doi.org/10.1002/cncr.25488 Cancer. 2010 Aug 24.
Retroviral expression of arginine decarboxylase attenuates oxidative burden in mouse cortical neural stem cells. Neural stem cells (NSCs) have the potential to integrate seamlessly into ... Bokara KK, Kwon KH, Nho Y, Lee WT, Park KA, Lee JE,http://dx.doi.org/10.1089/scd.2010.0312 Stem Cells Dev. 2010 Aug 24.
Immunocytological analysis of chromatin in isolated nuclei. All cells in a multicellular organism have the same genetic constitution, ... Pavlova P, Tessadori F, de Jong HJ, Fransz P,http://dx.doi.org/10.1007/978-1-60761-765-5_28 Methods Mol Biol. 2010;655:413-32.
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. Neutrophils trap and kill bacteria by forming highly decondensed chromatin ... Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y,http://dx.doi.org/10.1084/jem.20100239 J Exp Med. 2010 Aug 23.
Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells. Clonal expansion of virus-specific naive T cells during an acute viral ... Youngblood B, Davis CW, Ahmed R,http://dx.doi.org/10.1093/intimm/dxq437 Int Immunol. 2010 Aug 23.